A Formulation is the composition of a drug product that contains the active pharmaceutical ingredient (API) and other inactive ingredients. Formulation Development, it is important to use an effective methodology. Design of experiments (DOE) and statistical analysis have been applied widely to formulation development, and are useful in process optimization and process validation. There are many types of Formulations which includes Pharmaceutical Formulation, in pharmaceutics, is the process in which different chemical substances, including the active drug, are combined to produce a final medicinal product. For the Development Protein Formulations may require even more resources and effort than conventional small molecule pharmaceuticals. Herbal Formulations are not a simple task since many factors influence the biological efficacy and reproducible therapeutic effect. Cosmetics Formulations intended to be rubbed, sprinkled, or sprayed applied to the human body for altering the appearance without affecting structure or function. The goal of advancement in Vaccine Formulation is to generate a strong immune response to the administered antigens. Ayurvedic Formulations are based on plants, animals extract and minerals both in single ingredient drugs and compound formulations. Liquid Formulations are stored in vials, IV bags, ampoules, cartridges, and prefilled syringes. As with solid formulations, liquid formulations combine the drug product with a variety of compounds to ensure a stable active medication. Polymer Formulation can address certain unique properties without having to synthesize an entirely new molecular design. Formulation science deals with material science and physical chemistry joins to arrive an optimum combination of correct proportion of components. Formulation chemistry deals with manufacturing substances that do not react with each other, but have desirable properties as a mixture.